Specific PRP and PRP Gel Preparations

The Arthrex Angel System is a revolutionary production system for platelet-rich plasma (PRP) formulations which can be exactly tailored to the specific treatment needs of the patient. The Arthrex Angel System satisfies the three most important requirements for a modern PRP system: maximum exibility, easy handling, and a high level of safety.

Maximum Flexibility – One System for All PRP Applications

No matter which condition needs to be treated with PRP, with the Arthrex Angel System it is possible to tailor the PRP composition to the patient in question. The Arthrex Angel System gives the user control over the platelet, neutrophil and erythrocyte (RBC) levels in the PRP, thereby making it possible to match them to the indication and needs of the patient. So no more compromises have to be made in PRP therapy and the patients get the best solution possible – with just one system!

Easy Handling – PRP Preparation with just the push of a button

When the Arthrex Angel System is combined with Arthrex activAT, it is also possible to prepare platelet-rich brin gel (PRF gel), thereby expanding the range of applications.

No more cumbersome manual separation and transfer of the platelet-rich plasma fraction, where both the composition and yield of the PRP depended on the skill of the user. The Arthrex Angel System allows automatic push-button separation processing!

High Level of Safety – “Closed” PRP Preparation

Needles and open containers have no place in PRP preparation. The dangers of needlestick injury and microbial contamination are just too high! After automatic and fully closed separation in the Arthrex Angel System, the various fractions of the blood are collected in separate sterile containers and may be used directly or withdrawn through valves.

Fully Automatic, Closed Production of Indication-Specific PRP

the Arthrex Angel system is a revolutionary system for obtaining PRP preparations that can be tailored to relevant treatment needs. the three major requirements for a multifunctional PRP system are satisfied – maximum flexibility, easy handling, and a high level of safety.

FLEXIBILITY
the user can choose from various platelet and leukocyte concentrations and thereby tailor the PRP treatment to the needs of the patient. this is made possible by a proprietary 3-sensor technology which utilises the differences in light absorption of the various cell types. the Arthrex Angel system can handle volumes from 40 ml to 180 ml in a single cycle.

SIMPLICITY
the Arthrex Angel system has an intuitive user interface that enables production of the desired PRP formulation at the push of a button. there is no need to replace syringes or suspend buffy coats, as the Arthrex Angel system is fully automatic.

SAFETY
Since the Angel Processing set comes sterile and preassembled, the patient is protected against the risks of possible microbial contamination and the operator against any contact with the patient’s blood. the patient data from each processing cycle can be saved. subsequently, this data can be transferred quite easily since the Arthrex Angel system is equipped with both a USB and a LAN port.

Aesthetic Medicine

AREAS OF APPLICATION

(ANDROGENETIC) ALOPECIA:
PRP stimulates the proliferation and differentiation of stem cells in hair follicles. 8 Studies have shown a significant increase in hair diameter and hair density. 9, 10, 11

Wrinkles/Contours/Augmentation:
PRP has been used successfully in combination with fat grafts. Among other things it supports vascularisation and thus retention of fat grafts.

Skin Rejuvenation:
PRP stimulates the breakdown of light-damaged elements in the extracellular matrix and induces the synthesis of collagen, which improves dermal elasticity.  It has also been shown that PRP stimulates the body’s own hyaluronic acid synthesis, which results in a volume effect and enhances skin turgor. 14 studies have proved the effectiveness of PRP for facial and neck treatments without noticeable side effects. PRP can also be used in combination with fractional laser therapy.

Scarring:
PRP plays an active role in restructuring the extracellular matrix. the increased expression of matrix metalloproteinases brings about stimulation of dermal remodelling. 15 studies have shown that using PRP leads to an improvement in scarring / a reduction in severity (acne, traumatic scars).

Wounds / Ulcers:
PRP induces upregulation of regulatory active cell cycle proteins. The antibacterial effect of PRP has also been demonstrated. Studies have shown that PRP accelerates new tissue formation effectively for various wounds/ulcers.

Plastic Reconstructive Surgery
PRP can be used together with fat grafts for reconstructions, such as breast reconstructions. PRP supports vascularisation and thus retention of fat grafts and leads to improved retention of breast volume.

Skin Grafts (E.G. Facelifts, Abdominoplasties):
Studies have shown that PRP reduces postoperative pain and swelling and improves wound healing. PRP also reduces the formation of seroma and associated postoperative punctures.